Professor Saltzman talks about cell communication, specifically ligand-receptor interactions that are important in maintaining homeostasis in the body. Different types of receptors and ligands, the nature of their interactions and ways to apply this into developing drugs are discussed (eg. Aldopa, Taximofen, beta-blockers). Next, Professor Saltzman talks about kinases, phosphatases, cyclic AMP and the mechanism of switching protein states. Three categories of cell communication signals are introduced: autocrine, paracrine, and endocrine. Finally, an example of cell communication using regulation/response to blood sugar level is presented.
The course covers basic concepts of biomedical engineering and their connection with the spectrum of human activity. It serves as an introduction to the fundamental science and engineering on which biomedical engineering is based. Case studies of drugs and medical products illustrate the product development-product testing cycle, patent protection, and FDA approval. It is designed for science and non-science majors.
As one of the world's great universities, Yale traces its roots back to the early 1640s when colonial clergyman sought to establish a school in order to continue the tradition of European education within the Americas. Yale has now grown to educate over 11,000 students from over 100 countries on a 310-acre campus in New Haven, Connecticut. Within the school's 260 buildings are over 2,000 undergraduate programs in 65 departments taught by a distinguished faculty. As Academic Earth's first partner school, Yale has been a leader within the space of OpenCourseWare by consistently delivering on its esteemed mission to expand access to educational materials for all who wish to learn.