Enzyme Catalysis

Lecture Description

Course Description

This course deals primarily with equilibrium properties of macroscopic systems, basic thermodynamics, chemical equilibrium of reactions in gas and solution phase, and rates of chemical reactions.

Course Index

1. State of a system, 0th Law, Equation of State
2. Work, heat, first law
3. Internal energy, expansion work
4. Enthalpy
5. Adiabatic Changes
6. Thermochemistry
7. Calorimetry
8. Second Law
9. Entropy and the Clausius Inequality
10. Entropy and Irreversibility
11. Fundamental equation, Absolute S, Third Law
12. Criteria for Spontaneous Change
13. Gibbs Free Energy
14. Multicomponent Systems, Chemical Potential
15. Chemical Equilibrium
16. Temperature, Pressure, and Kp
17. Equilibrium: Application to Drug Design
18. Phase Equilibria - One Component
19. Clausius - Clapeyron Equation
20. Phase Equilibria - Two Components
21. Ideal Solutions
22. Non-ideal Solutions
23. Colligative Properties
24. Introduction to Statistical Mechanics
25. Partition Function (q) - Large N limit
26. Partition Function (Q) - many particles
27. Statistical Mechanics and discrete energy levels
28. Model Systems
29. Applications: Chemical and Phase Equilibria
30. Introduction to Reaction Kinetics
31. Complex Reactions and Mechanisms
32. Steady-state Equilibrium Approximations
33. Chain Reactions
34. Temperature Dependence, Ea, Catalysis
35. Enzyme Catalysis
36. Autocatalysis and Oscillators