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  1. The cultural transition from the romantic era of consumption to the era of tuberculosis derived not only from the germ theory of disease and the triumph of contagionism over anticontagionism, but also from political considerations. Worries over population decline and growing working-class militancy were aggravated by what now appeared to be a social disease, or a disease of poverty. One of the strategies deployed against the disease was...more

  2. In this lecture on feminist criticism, Professor Paul Fry uses Virginia Woolf's A Room of One's Own as a lens to and commentary on the flourishing of feminist criticism in the twentieth century. The structure and rhetoric of A Room of One's Own is extensively analyzed, as are its core considerations of female novelists such as Austen, Eliot, and the Brontës. The works of major feminist critics, such as Ann Douglas, Mary Ellman, Kate...more

  3. In this lecture, Professor Paul Fry turns his attention to the relationship between authorship and the psyche. Freud's meditations on the fundamental drives governing human behavior are read through the lens of literary critic Peter Brooks. The origins of Freud's work on the "pleasure principle" and his subsequent revision of it are charted, and the immediate and constant influence of Freudian thought on literary production is asserted....more

  4. The form of medicine that arose in fifth-century Greece, associated with the name of Hippocrates and later popularized by Galen, marked a major innovation in the treatment of disease. Unlike supernatural theories of disease, Hippocrates' method involved seeking the causes of illness in natural factors. This method rested upon an analogy between the order of the universe and the composition of the body's "humors." Health, on this view, was...more

  5. This lecture explains what an economic model is, and why it allows for counterfactual reasoning and often yields paradoxical conclusions. Typically, equilibrium is defined as the solution to a system of simultaneous equations. The most important economic model is that of supply and demand in one market, which was understood to some extent by the ancient Greeks and even by Shakespeare. That model accurately fits the experiment from the...more

  6. In the first half of the lecture, we consider the chain-store paradox. We discuss how to build the idea of reputation into game theory; in particular, in setting like this where a threat or promise would otherwise not be credible. The key idea is that players may not be completely certain about other players' payoffs or even their rationality. In the second half of the lecture, we stage a duel, a game of pre-emption. The key strategic...more

  7. In this lecture, Professor Paul Fry examines trends in African-American criticism through the lens of Henry Louis Gates, Jr. and Toni Morrison. A brief history of African-American literature and criticism is undertaken, and the relationship of both to feminist theory is explicated. The problems in cultural and identity studies of essentialism, "the identity queue," expropriation, and biology are surveyed, with particular attention paid to...more

  8. Continuing the examination of molecular orbital theory as a predictor of chemical reactivity, this lecture focuses on the close analogy among seemingly disparate organic chemistry reactions: acid-base, SN2 substitution, and E2 elimination. All these reactions involve breaking existing bonds where LUMOs have antibonding nodes while new bonds are being formed. The three-stage oxidation of ammonia by elemental chlorine is analyzed in the...more

  9. There is a longstanding debate over the origins of syphilis, in which arguments over how the disease arrived in Europe have historically been linked to racist and xenophobic ideologies as well as to scientific and historical research. Whatever its provenance, the major syphilis epidemic of the late sixteenth and early seventeenth centuries spread in the train of war, alongside Charles VIII of France's armies. Syphilis was distinguished...more

  10. Professor McBride begins by following Newton's admonition to search for the force law that describes chemical bonding. Neither direct (Hooke's Law) nor inverse (Coulomb, Gravity) dependence on distance will do - a composite like the Morse potential is needed. G. N. Lewis devised a "cubic-octet" theory based on the newly discovered electron, and developed it into a shared pair model to explain bonding. After discussing Lewis-dot notation...more

  11. This lecture introduces students to the study of psychology from an evolutionary perspective, the idea that like the body, natural selection has shaped the development of the human mind. Prominent arguments for and against the theory of natural selection and its relationship to human psychology are reviewed. Students will hear several examples of how studying mental phenomenon from an evolutionary perspective can help constrain theories...more

  12. Professor Shapiro explains the format and structure of the class during this opening session. He reviews the syllabus, and asks the central question of the course: What makes a government legitimate? He briefly explains the five ways to answer this question that he will focus on throughout the semester. The first three traditions are those of the Enlightenment: utilitarianism, Marxism, and social contract theory. The fourth and fifth...more