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Regulation of gene expression


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  1.   Loss of sensory or behavioural functions as a result of brain damage or dysfunction can clearly have a significant negative impact on quality of life.  What progress are we making towards repairing damaged brains and sense organs and treating mental disorders? This lecture will consider what therapeutic promise is currently offered by pharamacological, brain stimulation, brain training, neuroprosthetic (connecting artificial sensors to...more

  2. State-action Rewards, Finite Horizon MDPs, The Concept of Dynamical Systems, Examples of Dynamical Models, Linear Quadratic Regulation (LQR), Linearizing a Non-Linear Model, Computing Rewards, Riccati Equation

  3. March 4, 2009, Richard Morse states that coal is the largest growing source of energy and that regulation and policy are beginning to play a larger role in the economy of coal power. Morse also discusses the heavy reliance on coal by developing countries and the need to understand and evaluate all mitigation options.

  4. In this lecture on post-colonial theory, Professor Paul Fry explores the work of Edward Said and Homi K. Bhabha. The complicated origins, definitions, and limitations of the term "post-colonial" are outlined. Elaine Showalter's theory of the phasic development of female literary identity is applied to the expression of post-colonial identities. Crucial terms such as ambivalence, hybridity, and double consciousness are explained. The relati...more

  5. The Apostle Paul's description of the Jewish Law in his letter to the Galatians demotes from being an expression of Jewish faith to an object of idolatry and one that imprisons those who follow it. Paul is careful to nuance this position, however, in his letter to the Romans. In Romans, it seems that Paul is defending himself against charges of being antinomian. Perhaps Paul treads carefully in order to ensure that his deliverance of a don...more

  6. Genetics controls evolution. There are four major genetic systems, which are combinations of sexual/asexual and haploid/diploid. In all genetic systems, adaptive genetic change tends to start out slow, accelerate in the middle, and occur slowly at the end. Asexual haploids can change the fastest, while sexual diploids usually change the slowest. Gene frequencies in large populations only change if the population undergoes selection.

  7. Concepts covered in this lecture begin with the restoring force of a spring (Hooke's Law) which leads to an equation of motion that is characteristic of a simple harmonic oscillator (SHO). Using the small angle approximation, a similar expression is reached for a pendulum. To demonstrate that the period is independent of the mass of the bob, Professor Lewin places himself at the end of the 5 meter long cable and measures the period.

  8. Professor Shapiro guides the class through some practical applications of his theory of democratic justice. As applied to governing children, a sphere in which power-based hierarchy is inevitable, he circumscribes the role of the state as the fiduciary over children's basic interests and the role of parents as the fiduciaries over children's best interests. In other words, the state ensures the provision of the resources necessary for surv...more

  9. The lecture begins with an explanation of why Plato's Apology is the best introductory text to the study of political philosophy. The focus remains on the Apology as a symbol for the violation of free expression, with Socrates justifying his way of life as a philosopher and defending the utility of philosophy for political life.

  10. Environmental Politics and Law (EVST 255) The lecture reviews water law in the United States, and highlights challenges inherent in regulating water quality. Aging water infrastructure, pesticide and herbicide application, and surface water runoff all pose challenges in maintaining a clean drinking water supply. The lecture covers pesticide management through the Safe Drinking Water Act (SDWA). The management of pesticides and herbicide...more

  11. Environmental Politics and Law (EVST 255) The final lecture reviews topics discussed in previous lectures by imagining an ideal society.  Professor Wargo talks about success stories in land management in the Adirondacks and pesticide regulation, and notes ongoing challenges in food safety, drinking water quality, personal consumption, population control, and the creation of parks and protected areas.  He lectures about the fractured nat...more

  12. Reaction norms depict the range of phenotypes a single genotype can produce, depending on the environment. Reaction norms must fit within an organism's phylogenetic constraints. They can differ for different individuals within a population, but some traits differ very little based on the environment; some do not differ at all.