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Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
This introductory virology course emphasizes the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population. The molecular basis of alternative reproductive cycles, the interactions of viruses with host organisms, and how these lead to disease are presented with examples drawn from a set of representative animal and human viruses, although selected ...more
The MIT Biology Department core courses all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into mul...more
Laboratory that accompanies UC Berkeley General Biology I lecture course, which covers cell structure and function, molecular and organismal genetics, animal development, form and function.
General introduction to cell structure and function, molecular and organismal genetics, animal development, form and function.
Genetic Engineering in Medicine, Agriculture, & Law is a class that examines the historical and scientific study of genetic engineering in medicine, agriculture, and law, including examination of social, ethical, and legal issues raised by new technology. About the Professor: Dr. Bob Goldberg is a plant molecular biologist who specializes in the area of plant gene expression. The goal of his research has been to understand how plant cells ...more
The MIT Biology Department core courses all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into mul...more
This lecture is our first (of two) about integer data structure lower bounds. In particular, we'll prove that the min of van Emde Boas and fusion trees is an optimal (static) predecessor data structure up to a log log factor, assuming polynomial space. The exact trade-off (up to constant factors) is known, but messier; we'll see the bound but not prove it. In particular, it is known that the log log factor improvements are actually impossi...more
A perennial favorite is the idea of time travel. What would happen if we could go back in time and alter the future a la “Back to the Future”? The great narrative of the history of life has a complexity rife with subplots and twists, many of which we will never uncover. Yet somehow the story of life on Earth began with a prebiotic ooze and ended with the awe-inspiring diversity of life we see today – including us. But like any story, the ...more
Professor Saltzman continues his description of nephron anatomy, and the specific role of each part of the nephron in establishing concentration gradients to help in secretion and reabsorption of water, ions, nutrients and wastes. A number of molecular transport processes that produces urine from the initial ultra-filtrate, such as passive diffusion by concentration difference, osmosis, and active transport with sodium-potassium ATPase, ar...more
Professor Saltzman continues his presentation on DNA technology by discussing control of gene expression using two methods of RNA silencing: anti-sense therapy and RNA interference. Molecular cloning techniques to mass-produce proteins using plasmid, restriction enzymes, ligase, and antibiotic selection in bacteria are discussed. Steps and molecules involved in polymerase chain reaction are also described. Professor Saltzman explains how t...more
Professor Saltzman continues his presentation on DNA technology by discussing control of gene expression using two methods of RNA silencing: anti-sense therapy and RNA interference. Molecular cloning techniques to mass-produce proteins using plasmid, restriction enzymes, ligase, and antibiotic selection in bacteria are discussed. Steps and molecules involved in polymerase chain reaction are also described. Professor Saltzman explains how t...more
