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  1. The major market for the AIDS vaccine is in the developing world, says Francis, but there is significant demand in the United States with 40,000 new cases a year.  There are a lot of unknowns in the business climate in the United States affecting the profitability of a vaccine.  It is difficult to encourage investment when a blockbuster drugs would have a much higher rate of return, he adds.

  2. The global AIDS pandemic furnishes a case study for many of the themes addressed throughout the course. While in the developed West the disease largely afflicts concentrated high-risk groups such as intravenous drug users and the sexually promiscuous, in Southern Africa it is much more a generalized disease of poverty. In countries such as Botswana and Swaziland, the economic and social consequences of the disease have created a vicious...more

  3. Randy has learned from years of starting companies that he has developed an addiction to risk taking. A benefit of young companies is that it is easier to take risks because of the size. There may be nay-sayers, but Randy's advice is to ignore them and continue on with your plan.

  4. Bronfman argues that the problem with America is that while values of integrity, hard-work, the rule of law and meritocracy are exported, the advancement of opportunities is not. This is why Endeavor is such a powerful role model; it provides economic opportunities in countries where democracy cannot flourish. With the growing availability of opportunities he says, cultures change, countries evolve, and the world becomes a better and more...more

  5. This lecture completes the first half of the semester by analyzing three functional groups in terms of the interaction of localized atomic or pairwise orbitals. Many key properties of biological polypeptides derive from the mixing of such localized orbitals that we associate with "resonance" of the amide group. The acidity of carboxylic acids and the aggregation of methyl lithium into solvated tetramers can be understood in analogous...more

  6. Autodesk prices and packages its products differently in different countries. Bartz discusses how Autodesk has been successful doing business in emerging markets. She talks about the importance of looking at wage standards and labor standards of the country when selling global products like AutoCad across the world.

  7. Ringold talks about the decision to move away from being a technology based company at Affymax to applying the technology to pharma because of the relatively small life of a leading technology. Because of lack on internal infrastructure, they decided to sell the company and put it into the hands of a bigger company that had the infrastructure and expertise to use the technology. After a global search, Glaxo bought Affymax, he says.

  8. Francis talks about how after 9/11, the government became interested in vaccines.  Vaxgen shifted to making a small pox vaccine and an anthrax vaccine and has been very successful in these pursuits.  Unfortunately, AIDS was not named as an immediate concern and was but on the back burner. Due to the unwillingness of both the government and private businesses to provide funding, Francis has now decided that the AIDS vaccine cannot be...more

  9. Earl discusses the several challenges and mitigation strategies used when marketing to a variety of Asian countries. EA's strategy to overcome the IP protection problems is to take games online. He also discusses the need for different technology requirements to market in countries like South Korea where social networking is a key driver of sales.

  10. One of the principal myths concerning collaboration during World War II in France, as in other countries, is that the domestic collaborators did so despite themselves, or to prevent even greater atrocities. In fact, many French, Belgians, Hungarians, Poles, Dutch and others voluntarily and enthusiastically abetted the occupying Germans. This collaboration, inspired by anti-Semitism and xenophobia, often resulted in extremely zealous...more

  11. July 26, 2007 presentation by Craig Heller for the Stanford University Office of Science Outreach's Summer Science Lecture Series. Craig Heller, Professor of Biological Sciences, shares how and why this novel technique is being developed and its potential to improve the quality of human life and the body's performance.

  12. Andy Friere, Co-founder and CEO of Axialent, describes the people-first culture archetype, one of the five basic cultural archetypes into which organizations fall: 1) Achievement, 2) Innovation, 3) One team, 4) People-first or 5) Customer-focused. Specifically, Friere suggests that people-first cultures are focused on building and developing organizational members above other potential activities. Friere describes the behaviors, symbols...more