large margins
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If Fluidigm had not decided to market the crystallization chip, says Worthington, they would have developed a platform for doing large-scale parallel PCR. However, they decided against it because the market was already firmly established by major companies and Worthington was not optimistic about forming a partnership with a large company.
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According to Komisar, creating visibility and driving sales are two different tasks. Marketing channels are pretty well honed, but driving sales requires more attention. As an entrepreneur, you play a large part in creating the demand for your product and Google is not going to do that for you. You have to convince people that your product will save them money, he says.
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Dell explains how process is critical for organizing large numbers of people in a company, particular if it has grown rapidly. As part of its business development process, the company allows anyone to get involved in improving things they see could be done better. These improvements can be shared easily across the world, says Dell.
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Hemingway, Fitzgerald, Faulkner (AMST 246)Professor Wai Chee Dimock demonstrates how four of Fitzgerald's most famous short stories -- "The Rich Boy," "Babylon Revisited," "The Diamond as Big as the Ritz," and "Bernice Bobs Her Hair" -- represent "social types," generic identities that Fitzgerald explores as forms of social reality. She reads the dramatic tension in each of those stories as determined by the protagaonist's conformity to or...more
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How do investors gauge whether a company is one from a pool of thousands worth their resources? KPCB parter Beth Seidenberg shares her firm's five measures for financial fortitude. In this clip, she outlines leadership, and how this is the most important talisman of a growing enterprise's success. In addition, she discusses the importance of large, fast-growing, under-served markets, and KPCB's willingness to take risk with new technologie...more
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Rick Wallace shares the history of KLA-Tencor to show that it is important to follow one's business model. KLA revolutionized the industry by starting to charge for service instead of just offering it up for free. In order to enforce this, the founder had to risk losing IBM as a client. However, his bet paid off, and IBM finally agreed to pay for service. This has led to a large and profitable annuity stream for KLA-Tencor....more
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Systems consisting of pendulums and springs can freely oscillate at their natural frequencies (also called normal modes). When we expose a system to a wide spectrum of frequencies, the response will be very large at the normal mode frequencies (resonances) of that system. Examples include musical instruments (standing waves on violin strings and pressure waves in wind instruments), and torsional standing waves on a bridge driven by strong winds.
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Generic Lsearch - Prototype, Comparison Function, Implementation, Casting Void*S to Char*S to Compute Byte Offsets, Client Use of Generic Lsearch, Example of a Comparison Function for Integers, More Complicated Data Types and Lsearch- Example Using C-Strings, Comparison Function for Two C-Strings, With Arguments that Represent Char**S, Comparison Functions Where the Key is a Different Type than the Second Argument, Using a Pointer to a Str...more
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Genetics controls evolution. There are four major genetic systems, which are combinations of sexual/asexual and haploid/diploid. In all genetic systems, adaptive genetic change tends to start out slow, accelerate in the middle, and occur slowly at the end. Asexual haploids can change the fastest, while sexual diploids usually change the slowest. Gene frequencies in large populations only change if the population undergoes selection.
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Yock talks about how the hospitals make money on cardiac surgery, but they are concerned that the stents will take away the nice margins they have in cardiac surgery. This would mean loss of revenue for the hospital, he says.
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Tom Friel, Chairman of Heidrick and Struggles, discusses the challenges of building a great team and suggests that startups can attract great talent with a number of factors, including money, self-fulfillment, belief in the mission or belief in the founder. Friel argues that to attract and retain great talent, entrepreneurs should be generous with at least one or more of these factors and sufficient on the others. Furthermore, Friel adds o...more
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Until recently, the world population has been growing faster than exponentially. Although the growth rate has slowed somewhat, there are about 80 million more people each year and about 3 billion more will be added by 2050 (a 50% increase). Population will probably increase more beyond that. Such growth is unprecedented and we cannot predict its long-term effects. The environmental impact of this population increase is bound to be astronom...more
