Professor Saltzman reviews the concept of gene therapy, and gives some examples of where this is applied. Methods to help deliver DNA into cells using viruses and cationic lipids are discussed, as a way to overcome some challenges in gene therapy. Next, Professor Saltzman gives a brief introduction into bacterial and mammalian cell physiology. He describes the different tissues in the body, the cell development/differentiation process, the...more
Dr. Paul Ewald speaks about how several pathogenic viruses have evolved over time to break down the cell's barriers to several types of cancer. He suggests that further research will aid in the discovery of additional viruses linked to the causation of cancer. The lecture is concluded with a panel discussion with Gary Schoolnik and Stanley Falkow.
Molecular biology of prokaryotic and eukaryotic cells and their viruses. Mechanisms of DNA replication, transcription, translation. Structure of genes and chromosomes. Regulation of gene expression. Biochemical processes and principles in membrane structure and function, intracellular trafficking and subcellular compartmentation, cytoskeletal architecture, nucleocytoplasmic transport, signal transduction mechanisms, and cell cycle control.
Threats to privacy: cookies, forms, logs, and data recovery. Security risks: packet sniffing, passwords, phishing, hacking, viruses and worms, spyware, and zombies. Piracy: WaReZ and cracking.
Professor Marian Diamond. The functional anatomy of the human body as revealed by gross and microscopic examination. The Department of Integrative Biology offers a program of instruction that focuses on the integration of structure and function in the evolution of diverse biological systems. It investigates integration at all levels of organization from molecules to the biosphere, and in all taxa of organisms from viruses to higher plants...more
This introductory virology course emphasizes the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population. The molecular basis of alternative reproductive cycles, the interactions of viruses with host organisms, and how these lead to disease are presented with examples drawn from a set of representative animal and human viruses, although selected ...more
William Gelbart, Distinguished Professor of Chemistry and Biochemistry, University of California, Los Angeles, gave the 2010 Buhl Lecture at the Mellon College of Science at Carnegie Mellon University. His talk, entitled "Viruses From Scratch", discusses viruses from a physical point of view, emphasizing their unique simplicity and what they all have in common.
Introduction to viruses.