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The Tuskegee Experiment

By Frank Snowden - Yale
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Lecture Description

The Tuskegee Syphilis Study, carried out in Macon, Alabama, from 1932 to 1972, is a notorious episode in the checkered history of medical experimentation. In one of the most economically disadvantaged parts of the U.S., researchers deceived a group of 399 black male syphilitics into participating in a study with no therapeutic value. These "volunteers" were not treated as patients, but rather as experimental subjects, or walking cadavers. Even after the development of penicillin, the Tuskegee group was denied effective treatment. Despite regularly published scholarly articles, forty years passed before there was any protest in the medical community. The aftereffects of the study, along with the suffering of its victims, include a series of congressional investigations, the drafting of medical ethics guidelines, and the establishment of independent review boards.

Course Description

Course Index

  1. Introduction to the Course
  2. Classical Views of Disease: Hippocrates, Galen, and Humoralism
  3. Plague (I): Pestilence as Disease
  4. Plague (II): Responses and Measures
  5. Plague (III): Illustrations and Conclusions
  6. Smallpox (I): 'The Speckled Monster'
  7. Smallpox (II): Jenner, Vaccination, and Eradication
  8. Nineteenth-Century Medicine: The Paris School of Medicine
  9. Asiatic Cholera (I): Personal Reflections
  10. Asiatic Cholera (II): Five Pandemics
  11. The Sanitary Movement and the 'Filth Theory of Disease'
  12. Syphilis: From the "Great Pox" to the Modern Version
  13. Contagionism versus Anticontagionism
  14. The Germ Theory of Disease
  15. Tropical Medicine as a Discipline
  16. Malaria (I): The Case of Italy
  17. Malaria (II): The Global Challenge
  18. Tuberculosis (I): The Era of Consumption
  19. Tuberculosis (II): After Robert Koch
  20. Pandemic Influenza
  21. The Tuskegee Experiment
  22. AIDS (I)
  23. AIDS (II)
  24. Poliomyelitis: Problems of Eradication
  25. SARS, Avian Inluenza, and Swine Flu: Lessons and Prospects
  26. Final Q&A